Born in Nagasaki/Japan in 1969, Yasuko Yamaguchi studied composition at the Tokyo National University of Fine Arts and Music with Akira Kitamura, Hideo Kobayashi and Michio Mamiya. In 1997 she continued her studies at Robert Schumann Hochschule Düsseldorf with Manfred Trojahn, where Yasuko Yamaguchi received a Diploma in composition in 2000.
She received awards at the 13th Kanagawa Prefectural Composition Competition for Choral Works (1989) and at the 8th Composition Competition for Young Composers of the Japanese Society for Contemporary Music (1992). In 2005 she received the advancement award of the state capital Düsseldorf for music, in 2016 the scholarship of Künstlerhof Schreyahn. In 2018 Yasuko Yamaguchi hold the scholarship of the State Ministry of Cultural Affairs at the German Study Center in Venice (Centro Tedesco di Studi Veneziani). In the summer of 2022 she lived in Bellwald (Switzerland) as a scholarship holder of artbellwald.ch. Furthermore, Yasuko Yamaguchi obtained grants from Musikfonds Berlin und German Music Council.